The KressWorks Foundation Systematic Treatment Methodology Proof of Principle validation

July 18, 2014 9:14:33 PM EDT

Posted by:Jim Kress

The KressWorks Foundation Systematic Treatment Methodology (STM) approach has been validated through the excellent work of X-Y Zhang, MR Birtwistle and JM Gallo at Department of Pharmacology and Systems Therapeutics, Icahn School of Medicine at Mount Sinai, New York, They have provided proof of principle of the PK/ePD method developed based on biochemical mechanisms and produced unique drug combination regimens that support systems pharmacological approaches in translational medicine.

This methodology is at the core of our STM and the work of Zhang et al clearly demonstrates we are on the right path.

Their work can be found at: "A General Network Pharmacodynamic Model–Based Design Pipeline for Customized Cancer Therapy Applied to the VEGFR Pathway". Pharmacometrics & Systems Pharmacology (2014) 3, e92; doi:10.1038/psp.2013.65 © 2014 ASCPT

See our presentation materials for more information on the STM.  A copy of the paper by X-Y Zhang, MR Birtwistle and JM Gallo can found here

Detroit's Premier Business Magazine publishes a great article about the KressWorks Foundation

September 11, 2014 5:31:17 PM EDT

Posted by:Jim Kress

Detroit's Premier Business Magazine, DBusiness Magazine, published a great article about the KressWorks Foundation on September 8, 2014.

You can find a link to it here.

It ended with a great summary:

“In today’s cancer research and clinical institutions, we find a proliferation of the pursuit of answers to individual questions, but we believe a coordinated systems engineering approach is the key for developing a cure.”

October 15th Fundraiser for The KressWorks Foundation

October 6, 2015 10:10:43 PM EDT

Posted by:Jim Kress

The KressWorks Foundation will host a fun and informative fundraiser from 6 to 9 pm at the Rust Belt, 22801 Woodward in Ferndale, featuring guest speaker and cancer survivor Ms. LaHoma Caudill, reigning Ms. California for 2015, Mrs. California 2012, and 3rd runner up in Ms. America 2015. 
    LaHoma will talk about her ordeal with cancer and the importance of supporting organizations like The KressWorks Foundation that are working to find a cure for the disease. She will also do a meet and greet and sign autographs. Also at the event will be noted author Trudy Krisher, whose daughter is a Ewing’s Sarcoma survivor, a rare event. Her widely praised book, Kathy’s Hats, chronicles her daughter’s ordeal in battling Ewing’s.
    Tickets for the event are $200 per person or $350 per couple and include passed appetizers, beer and wine.  Dr. Jim Kress will also be giving a brief presentation on the motivation, goals, objectives, and accomplishments of the KressWorks Foundation and its work with Ewing’s Sarcoma. Only 200 tickets are available and can be purchased by RSVP to Jamie Cremin at 646/207-3174 or by October 8th.